ZOVOILIS LAB
Publications
1. Saville L, Cheng Y, Gollen B, Mitchell L, Stuart-Edwards M, Haight T, Mohajerani M, Zovoilis A. NERD-seq: A novel approach of Nanopore direct RNA sequencing that expands representation of non-coding RNAs. Submitted.
2. Cheng Y, Saville L, Gollen B, Alvarez-Veronesi A, Joseph J, Mohajerani M, Zovoilis A. (2021). Increased Alu RNA processing in Alzheimer brains is linked to gene expression change. EMBO Reports. doi: 10.15252/embr.202052255
Available online: https://www.embopress.org/doi/10.15252/embr.202052255
3. Mitchell L, Turner C, Saville L, Cheng Y, Haight T, Roy R, Metz G, Mohajerani M, Zovoilis A. Differential adenosine to inosine RNA editing of SINE B2 non-coding RNAs in mouse unveils a novel type of epi-transcriptome response to amyloid beta neuro-toxicity. Submitted.
4. Cheng Y, Saville L, Gollen B, Isaac C, Belay A, Mehla J, Patel K, Thakor N, Mohajerani M, Zovoilis A. (2020). Increased processing of SINE B2 non coding RNAs unveils a novel type of transcriptome de-regulation underlying amyloid beta neuro-pathology. eLife 2020;9:e61265
Available online: https://elifesciences.org/articles/61265
5. Hernandez A #, Zovoilis A #, Rojas C# (#co-leading authors), Han L, Bujisic B, Lee JT. (2020). B2 and ALU retrotransposons are self-cleaving RNAs whose activity is enhanced by EZH2. PNAS, 117, 415-425.
Available online: https://www.pnas.org/content/117/1/415
6. Bressler K, Ross J, Ilnytskyy S, Vanden Dungen K, Taylor K, Patel K, Zovoilis A, Kovalchuk I, Thakor N. (2021). Depletion of eukaryotic initiation factor 5B (eIF5B) reprograms the cellular transcriptome and leads to activation of endoplasmic reticulum (ER) stress and c-Jun N-terminal kinase (JNK). Cell Stress Chaperones, 26:253-264.
7. Steinkey R, Moat J, Gannon V, Zovoilis A, Laing C. (2020). Application of artificial intelligence to the in silico assessment of antimicrobial resistance and risks to human and animal health presented by priority enteric bacterial pathogens. Can Commun Dis Rep, 46(6), 180-185.
8. Razmara P, Imbery J, Koide E, Helbing C, Wiseman S, Gauthier P, Bray D, Needham M, Haight T, Zovoilis A, Pyle G. Mechanism of copper nanoparticle toxicity in rainbow trout olfactory mucosa. Submitted.
9. Isaac C, Patel T, Zovoilis A. (2017). Non-coding RNAs in Virology: An RNA genomics approach. Biotechnology and Genetic Engineering Reviews, 34, 94-106.
10. Zovoilis A, Cifuentes-Rojas C, Chu HP, Hernandez AJ and Lee JT. (2016). Destabilization of B2 RNA by EZH2 activates the stress response. Cell, 167(7), 1788-1802.
11. Zovoilis A, Mungall A, Moore R, Varhol R, Chu A, Wong T, Marra M, Jones SJ. (2014). The expression level of small non-coding RNAs derived from the first exon of protein coding genes is predictive of cancer status. EMBO Reports, 15(4), 402-410.
12. Pantazi A, Zovoilis A#; # corresponding author. (2013). Vector-free methods formanipulating miRNA activity in vitro and in vivo. Methods Mol Biol, 936, 231-245.
13. Agis-BalboaRC, Arcos-Diaz D, Wittnam J, Govindarajan N, Blom K, Burkhardt S, Haladyniak U, Agbemenyah HY, Salinas-Riester G, Opitz L, Zovoilis A, Sananbenesi F, Fischer A. (2011). Ahippocampal IGF-II pathway regulates the extinction of fear memories. EMBO Journal, 30(19), 4071-4083.
14. Liao B, Bao X, Liu L, Feng S, Zovoilis A, Liu W, Xue Y, Cai J, Guo X, Qin B, Zhang R, Wu J, Lai L, Teng M, Niu L, Zhang B, Esteban MA, Pei D. (2011). Micrornacluster 302-367 enhances somatic cell reprogramming by accelerating amesenchymal-to-epithelial transition. J Biol Chem, 286(19), 17359-17364.
15. Zovoilis A, Agbemenyah HY, Agis-Balboa RC, Stilling RM, Edbauer D, Rao P, Farinelli L, Delalle I, Schmitt A, Falkai P, Bahari-Javan S, Burkhardt S, Sananbenesi F, Fischer A. (2011). MicroRNA 34c is anovel target to treat dementias. EMBO Journal, 30(20), 4299-4308.
16. #joint first authorship; Peleg S#, Sananbenesi F#, Zovoilis A#, Burkhardt S, Bahari-Javan S, Agis-Balboa RC, Cota P, Wittnam JL, Gogol-Doering A, Opitz L, Salinas-Riester G, Dettenhofer M, Kang H, Farinelli L, Chen W, Fischer A. (2010). Altered histone acetylation is associated with age-dependent memory impairmentin mice. Science, 328(5986), 753-756.
17. Zovoilis A#, Pantazi A, Smorag L, Opitz L, Salinas-Riester G, Wolf M, Zechner U, Holubowska A, Stewart C, Engel W. #corresponding author. (2010). Embryonic stem cellrelated miRNAs are involved in differentiation of pluripotent cells originatingfrom the germ line. Mol Hum Reprod, 16(11), 793-803.
18. Zechner U, Nolte J, Wolf M, Shirneshan K, Hajj NE, Weise D, Kaltwasser B, Zovoilis A, Haaf T, Engel W. (2009). Comparative methylation profiles and telomerase biologyof mouse multipotent adult germline stem cells and embryonic stem cells. Mol Hum Reprod, 15(6), 345-353.
19. Zovoilis A#, Smorag L, Pantazi A, Engel W. # corresponding author. (2009). Members of the miR-290 cluster modulate in vitro differentiation ofmouse embryonic stem cells. Differentiation, 78(2-3), 69-78.
20. Zovoilis A#, Nolte J, Drusenheimer N, Zechner U, Hada H, Guan K, Hasenfuss G, Nayernia K, Engel W. # corresponding author. (2008). Multipotent adult germline stem cells and embryonic stem cellshave similar microRNA profiles. Mol Hum Reprod, 14, 521-529.